• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    POSITIVE EXPIRATORY PRESSURE DEVICE AND METHOD OF PROVIDING A PATIENT'S AIRWAY CLEARING THERAPY A method of providing therapy for clearing a patient's airway includes receiving a stream of exhaled air from the patient into a chamber, creating a back pressure in the chamber (10) in response to reception of the exhaled air stream, the opening of a one-way valve, such as a magnetic duckbill valve 926), located downstream of the chamber only in response to the back pressure which is at least equal to a certain predetermined level, generating a vibratory effect downstream of the one-way valve, for example, using a vibrating ball check valve (32) when the one-way valve is opened in response to the air stream exhaled through it, and the distribution of a percussion sensation to the patient through the chamber in response to the vibratory effect.
    公开号:BR112013006247B1
    申请号:R112013006247-9
    申请日:2011-09-15
    公开日:2021-05-04
    发明作者:Dirk Ernest Von Hollen；Christopher John Brooks
    申请人:Koninklijke Philips N.V.；
    IPC主号:
    专利说明:

    [001] The present invention relates to the treatment of lung diseases, such as cystic fibrosis, in which mucus secretion accumulates in the lungs, and in particular to a positive expiratory pressure (PEP) vibratory device for use in clearing of the lungs of said secretions.
    [002] A number of respiratory conditions in which the patient experiences large accumulations of mucus in the lungs are known. One of these respiratory conditions is cystic fibrosis. Cystic fibrosis is an inherited and progressively debilitating disease in which a defective gene causes impaired mucociliary transport in the lungs, which causes chronic pulmonary obstruction, inflammation, and infection. Thus, it is important that people who suffer from such conditions unclog their airways, and that said people spend a significant amount of time trying to do so.
    [003] A number of airway clearance techniques are well known. Said techniques include manual chest physiotherapy (CPT), postural drainage, breathing exercises and coughing. Many people also use an airway clearance device to help with the task of clearing their airway. A number of such devices are known. One type of airway clearance device is known as a positive expiratory pressure (PEP) device. A PEP device is typically a small handheld device with a mouthpiece and a chamber that includes a one-way valve that allows air to easily flow during inspiration, but creates resistance during expiration. To clear the lungs using a PEP device, the patient inhales and exhales through the device several times and then blows out to remove loose mucus. Another related airway clearance device is known as a positive expiratory pressure vibrating (or vibrating) device. Vibrating (or vibrating) PEP devices work in the same way as PEP devices, except they also provide vibration to the patient's lungs to help stir loose mucus.
    [004] Since said techniques and devices have been successful in treating respiratory conditions such as cystic fibrosis, there is room for improvement in this area.
    [005] In one embodiment, a positive expiratory pressure device is provided that includes a chamber structured to receive a stream of expired air from a patient, the chamber with a fluid pathway passing through it, a magnetic duckbill valve provided along the fluid path, the magnetic duckbill valve having a first support wall of a series of first magnets with a first polarity and a second support wall of a series of second magnet with a second polarity opposite to the first polarity, the first magnets and second magnets being configured to create an opening resistance breaking force in the magnetic duckbill valve, in which the magnetic duckbill valve is structured to open only in response to at least a certain pressure of return that is created in the chamber, and a vibrating ball check valve provided along the fluid path downstream of the magnetic duckbill valve.
    [006] In another embodiment, a positive expiratory pressure device is provided that includes a chamber structured to receive a stream of expired air from a patient, a one-way valve provided downstream of the chamber, in which the one-way valve is structured to open only in response to at least a certain back pressure that is created in the chamber, and a vibrating ball check valve provided downstream of the one-way valve, in which the chamber, one-way valve and vibrating ball check valve are provided to the along a linear flow fluid pathway.
    [007] In yet another embodiment, a method of providing a therapy for clearing a patient's airway is provided that includes receiving a stream of expired air from the patient in a chamber, creating a back pressure in the chamber. in response to receiving the exhaled air stream, opening a one-way valve located downstream of the chamber only in response to back pressure that is at least equal to a certain predetermined level, generating a vibratory effect downstream of the one-way valve when the one-way valve is opened, and in response to the current of exhaled air passing through it, and the delivery of a percussion sensation to the patient through the chamber in response to the vibratory effect.
    [008] These and other objects, aspects and characteristics of the present invention, as well as the methods of operation and functions of the related elements of the structure and the combination of parts and manufacturing economies, will become more evident after consideration of the following description and of the appended claims with reference to the accompanying drawings, all of which form part of this specification, in which like reference numerals designate corresponding parts in the various figures. It is to be expressly understood, however, that the drawings are for illustrative and descriptive purposes only, and are not intended as a definition of the limits of the invention. As used in the specification and claims, the singular form of “a”, “an”, “the” and “a” includes plural referents, unless the context clearly indicates otherwise.
    [009] FIGURE 1 is a schematic cross-sectional diagram of a positive expiratory pressure (PEP) vibratory device in accordance with an exemplary embodiment of the present invention.
    [010] FIGURE 2 is a schematic cross-sectional diagram of a positive expiratory pressure (PEP) vibratory device of FIGURE 1 showing its operation during patient inspiration;
    [011] FIGURE 3 is a schematic cross-sectional diagram of a positive expiratory pressure (PEP) vibratory device of FIGURE 1 showing its operation during patient expiration; and
    [012] FIGURES 4 and 5 are isometric views of different embodiments of a magnetic duckbill valve that can form a part of the positive expiratory pressure (PEP) vibratory device of FIGURE 1.
    [013] Directional phrases used here, such as, for example, and without limitation, from above, below, left, right, top, bottom, front, rear, and their derivatives, refer to the orientation of the elements shown in the drawings. , and are not limiting of the claims, unless expressly stated herein.
    [014] As used herein, the statement that two or more parts or components are "coupled" must mean that, together, the parts are joined or operate together, either directly or through one or more intermediate parts or components.
    [015] As used here, the statement that two or more parts or components are "coupled" must mean that, together, the parts are joined or operate together, either directly or through one or more intermediate parts or components.
    [016] As used here, the term “number” shall mean one or an integer greater than one (ie, a plurality).
    [017] FIGURE 1 is a schematic cross-sectional diagram of a positive expiratory pressure (PEP) vibratory device 2 according to an exemplary embodiment of the present invention. FIGURE 2 is a schematic cross-sectional diagram of the PEP 2 vibratory device showing its operation during patient inspiration, and FIGURE 3 is a schematic cross-sectional diagram of the PEP 2 vibratory device showing its operation during expiration of the patient.
    [018] The PEP vibratory device 2 includes a mouthpiece portion 4. The mouthpiece portion 4 is a patient interface that is structured to allow the patient to place their mouth on the first end 6 of it and inhale and exhale through the vibrating device of PEP 2. In the exemplary embodiment, the nozzle portion 4 is made of injection molded plastic.
    [019] The PEP vibratory device 2 further includes an air inlet chamber 10, a magnetic duckbill chamber assembly 20, and a vibrating ball check valve assembly 32. The structure and function of each of the air inlet chamber 10, magnetic duckbill chamber assembly 20, and vibrating ball check valve assembly 32 are described in detail below.
    [020] As seen in FIGURES 1 to 3, the first end 12 of the air inlet chamber 10 is coupled to the second end 8 of the nozzle portion 4. The air inlet chamber 10 comprises a built-in check valve assembly that allows air to be drawn into the longitudinal fluid pathway 14 of the PEP vibratory device 2 when the patient inhales. In the exemplary embodiment, air inlet chamber 10, as well as nozzle portion 4, is fabricated from injection molded plastic (in an alternative embodiment, air inlet chamber 10 and nozzle portion 4 are molded as a frame. single and integrated). In the illustrated embodiment, the check valve 16 is provided in the inlet opening tube 18 of the air inlet chamber 10. The inlet opening tube 18 is oriented perpendicularly to the longitudinal fluid path 14. In a non-limiting embodiment in particular, check valve 16 is a compatible elastomeric disc that will deform inwardly and open with the vacuum pressure created by the patient's inspiration to allow air to freely flow in the patient's airway through the air inlet chamber 10 and the nozzle portion 4 (FIGURE 2). After the patient expires (FIGURE 3), the expiratory pressure will close the check valve 16, seal the air inlet chamber 10, and create a positive pressure built in the air inlet chamber 10. The positive pressure built in the air inlet chamber 10. Air inlet 10 will affect magnetic duckbill chamber assembly 20 and vibratory ball check valve assembly 32 of PEP vibratory device 2 in the manner described in detail below.
    [021] As seen in FIGURES 1 to 3, the first end 22 of the magnetic duckbill chamber assembly 20 is coupled to the second end 24 of the air inlet chamber 10. The magnetic duckbill chamber assembly 20 retains and seals the magnetic duckbill valve 26 in the air inlet chamber 10. The magnetic duckbill valve 26 is a one-way duckbill valve that has a series of skewed mini-magnets 28 attached to the leading edges of each lip or wall 30A , 30B of it (magnets 28 attached to wall 30A have a polarity that is opposite to the polarity of magnets 28 attached to wall 30B). The magnets 28 create a controlled opening resistance force on the magnetic duckbill valve 26. This opening force (i) will only allow the magnetic duckbill valve 26 to snap open when the back pressure is sufficient (greater than a certain predetermined amount - that is, an opening pressure) is reached in the air inlet chamber 10 due to the patient's exhalation (FIGURE 3), and (ii) will cause the magnetic duckbill valve 26 to quickly snap closed when the pressure in air inlet chamber 10 drops (below the predetermined set pressure) at the patient's expiration end. In the exemplary embodiment, magnets 28 are nickel-plated neodymium magnets that are 2 mm in diameter and 1 mm in thickness, and each has a maximum energy product of 37.46 megaGauss-Oersteds (MGOe). The patient's sensation after opening the magnetic duckbill valve 26 is (i) a rapid drop or change in pressure before the start of actuation of the vibratory ball check valve assembly 32 described in detail below, and (ii) a closing pressure set at the end of the patient's expiration. In the exemplary embodiment, the portions of the magnetic duckbill chamber assembly 20 in addition to the magnetic duckbill valve 26 are fabricated from injection molded plastic.
    [022] FIGURE 4 is an isometric view of a non-limiting example embodiment in particular of the magnetic duckbill valve 26, marked as magnetic duckbill valve 26'. As seen in FIGURE 4, each wall 30A', 30B' of magnetic duckbill valve 26' includes integral pockets 34 for retaining magnets 28 therein. In addition, each wall 30A', 30B' of the magnetic duckbill valve 26' is a flat structure which makes the magnetic duckbill valve 26' the shape of a straight conical valve.
    [023] FIGURE 5 is an isometric view of an alternative embodiment of non-limiting example in particular of the magnetic duckbill valve 26, marked as magnetic duckbill valve 26'. As seen in FIGURE 4, each wall 30A", 30B" of the 26" magnetic duckbill valve includes integral pockets 34 for retaining magnets 28 therein. In addition, each wall 30A", 30B" of the 26" magnetic duckbill valve includes a flat rectangular slanted portion 36 coupled to the tapered main wall portion 38. When the 26" magnetic duckbill valve and the slanted portions 36 engage one another and together they form the flat lip sealing surface 39.
    [024] The PEP vibratory device 2 further includes a vibrating ball check valve assembly 32 connected to the second end 40 of the magnetic duckbill chamber assembly 20. The vibrating ball check valve assembly 32 includes an inlet of conical receptive air (e.g. conical in shape) 42, a circular valve seat 44 at the air inlet end 42, a chamber 46, a perforated cap element 48, a damping ring 50 (made of an elastomeric material, such as rubber), incorporated cap element 48, and a spherical element 52 provided in chamber 46. In the exemplary embodiment, spherical element 52 is made of polypropylene. The air inlet 42 increases the velocity of the patient's exhaled air to displace the ball member 52 of the valve seat 44 in response to it (FIGURE 3). As the ball member 52 is pushed out of the valve seat 44, a pressure drop occurs which creates a vacuum, the Bernoulli effect, and sucks the ball member 52 back into the valve seat 44. the damping ring 50 acts as a spring which, upon impact with the spherical element 52, forces it back towards the valve seat 44 (thus the damping ring 50 works in conjunction with the vacuum to accelerate the retraction. chamber sealing 46). Once the patient expires on the PEP vibratory device 2 and the magnetic duckbill valve 26 is forced open, this process repeats a series of times and creates an oscillating vibratory effect that provides the patient with a percussive sensation through of PEP 2 vibrating device, which helps dislodge mucus from the patient's airways. The vibration and percussion sensation will continue until exhalation ends and the magnetic duckbill valve 26 snaps closed as a result of pressure within the air inlet chamber 10 falling below the set pressure. In the exemplary embodiment, the vibrating ball check valve assembly 32 (in addition to the ball member 52 and inner rubber damping ring 50) is fabricated from injection molded plastic.
    [025] Thus, the PEP 2 vibrating device is a tool that can be used by patients, such as patients with cystic fibrosis, to help unblock their airways, and provide resistance and vibration during expiration. The present invention can also be applied to airway clearance devices for Respiratory Drug Delivery (RDD) or Rate of Heat Change (HRC), and can also be applied to nebulizers and other inhaler-type devices.
    [026] Although the invention has been described in detail for purposes of illustration based on what is currently considered to be the most practical and preferred embodiments, it should be understood that said details are for that purpose only and that the invention is not limited to the disclosed realizations, but to the contrary, is intended to cover modifications and equivalent provisions that are within the spirit and scope of the appended claims. For example, it is to be understood that the present invention contemplates that, as far as possible, one or more features of any one embodiment may be combined with one or more features of any other embodiment.
    权利要求:
    Claims (7)
    [0001]
    1. POSITIVE EXPIRATORY PRESSURE DEVICE (2), characterized in that it comprises: a chamber (10) structured to receive a stream of expired air from a patient, the chamber with a fluid pathway (14) passing through it, a nozzle valve duck valve (26) provided along the fluid path, the magnetic duck nozzle valve (26) having a first wall (30A) supporting a series of first magnets (28) with a first polarity and a second wall ( 30B) supporting a series of second magnets (28) with a second polarity opposite the first polarity, the first magnets (28) and second magnets (28) being configured to create an opening resistance breaking force at the magnetic duckbill valve, in which the magnetic duckbill valve is structured to open only in response to at least a certain back pressure that is created in the chamber (10), and a vibrating ball check valve (32) provided along the fluid path downstream of the magnetic duckbill valve.
    [0002]
    2. POSITIVE EXPIRATORY PRESSURE DEVICE (2), according to claim 1, characterized in that the chamber comprises an air inlet chamber (10) with an air inlet opening (18) oriented perpendicularly to the fluid pathway (14) , the air inlet opening (18) with a check valve (16) structured to allow only fluid flow in the air inlet opening (18).
    [0003]
    3. POSITIVE EXPIRATORY PRESSURE DEVICE (2), according to claim 2, characterized in that it further comprises a nozzle portion (4) coupled to the first end (12) of the air inlet chamber, the valve being a magnetic duckbill (26) provided in a magnetic duckbill chamber assembly (20) coupled to a second end (24) of the air inlet chamber.
    [0004]
    4. POSITIVE EXPIRATORY PRESSURE DEVICE (2), according to claim 2, characterized in that the fluid path (14) is a longitudinal fluid path provided along a longitudinal axis of the positive expiratory pressure device (2).
    [0005]
    5. POSITIVE EXPIRATORY PRESSURE DEVICE (2) according to claim 3, characterized in that the vibrating ball check valve (32) is provided as part of a vibrating ball check valve assembly (20), in which a first one end of the vibrating ball check valve assembly (20) is coupled to an outlet end of the magnetic duckbill valve assembly (20), wherein the vibrating ball check valve assembly (20) includes a tapered opening (42 ) provided at the first end thereof, a valve seat (44) provided at one end of the conical opening (42), a second chamber (46) provided adjacent the valve seat (44), and a spherical element (52) provided in the second chamber (46), the spherical element (52) being structured to move within the second chamber (46) and intermittently engage the valve seat (44).
    [0006]
    6. POSITIVE EXPIRATORY PRESSURE DEVICE (2), according to claim 5, characterized in that the vibrating ball check valve (20) includes a damping ring element (50) positioned in the second chamber (46) opposite the seat of valve (44) wherein the ball member (52) is structured to intermittently engage the cushion ring member (50).
    [0007]
    7. POSITIVE EXPIRATORY PRESSURE DEVICE (2), according to claim 6, characterized in that the damping ring element (50) is made of an elastomeric material.
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    法律状态:
    2020-06-30| B06F| Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]|
    2020-08-18| B25D| Requested change of name of applicant approved|Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
    2020-09-08| B25G| Requested change of headquarter approved|Owner name: KONINKLIJKE PHILIPS N.V. (NL) |
    2020-10-06| B06U| Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]|
    2021-02-23| B09A| Decision: intention to grant [chapter 9.1 patent gazette]|
    2021-05-04| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/09/2011, OBSERVADAS AS CONDICOES LEGAIS. |
    优先权:
    申请号 | 申请日 | 专利标题
    US38474510P| true| 2010-09-21|2010-09-21|
    US61/384,745|2010-09-21|
    PCT/IB2011/054038|WO2012038864A2|2010-09-21|2011-09-15|Vibratory positive expiratory pressure device|
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